Ultra-Resolution Microscopy

GO BEYOND IMAGING

INTO MICROVASCULAR BIOLOGY

From visualizing microcirculation to

exploring the biology of disease.

URM is VINNO’s integrated implementation of ultrasound localization microscopy.

It localizes and tracks intravascular microbubbles across ultrafast CEUS frames to reconstruct and quantify microvascular architecture and flow.

ULTRAFAST PLATFORM

Up to 500 fps contrast imaging supports microbubble localization and trajectory tracking.

CEUS perfusion and URM microvascular detail, displayed side by side from one contrast injection.

Transplant Kidney (CEUS + URM Density)

URM uses ultrafast CEUS acquisition and microbubble tracking to reconstruct microvascular structure and flow, generating quantitative metrics beyond conventional CEUS.

Illustrative workflow. Motion checks apply throughout acquistion and reconstruction.

URM quantifies microvascular architecture and flow to support research into disease-related vascular phenotypes and candidate imaging biomarkers.

COMPREHENSIVE QUANTIFICATION

Morphology: vessel density, tortuosity, angle, curvature map and complexity. Hemodynamics: velocity and flow direction and dynamic map. Integrated assessment: perfusion index and vessel entropy.

VINNO ULTRAGLO

ROI-based glomerular counting and density analysis for renal research.

60 PUBLICATIONS

(to be updated)

Human studies · Preclinical research · Methods ·

Consensus · Reviews · Commentaries

From microvascular imaging to clinical insight.

Access selected clinical publications, clinical image gallery and hear from experts.

MULTICENTER BREAST RESEARCH

742 PATIENTS

12 HOSPITALS

External validation across 11 centers Standardized URM workflow across all centers

HUMAN CLINICAL RESEARCH ACROSS MULTIPLE SPECIALTIES BREAST,

LYMPH NODES & SOFT TISSUE

Breast lesions · Nodal metastasis Lymphoma ·

Superficial lymph-node lesions ·

Rare soft-tissue tumor

VStation Lab for URM research analysis

Review compatible URM datasets offline, apply a consistent ROI strategy and organize quantitative results for research. Offline analysis can help keep the ultrasound system available for scanning.

Why VStation Lab?

Keep the scanner available Run URM analysis offline so clinical scanning workflow is not interrupted. Batch analysis for efficiency Process multiple cases more efficiently for research datasets and follow-up review. Standardized reporting & export Generate consistent outputs and reports to streamline documentation and data sharing.

Same outputs as on ultrasound system, more efficient for research review

Typical workflow

Import → Analyze → Measure → Compare → Export